GPR85

Across TCGA cell cohorts, GPR85 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,117 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR85-associated GO terms across cancer lineages are Interleukin-9-mediated signaling pathway, Cellular response to interleukin-9, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with GPR85 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPR85-to-partner and partner-to-GPR85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interleukin-9-mediated signaling pathway grouped by GPR85-low versus GPR85-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR85→partner) and Y-score (partner→GPR85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Interleukin-9-mediated signaling pathway →	+0.178	+1.070	.002	.007	3	7
BLOOD_Lymphoma	Cellular response to interleukin-9 →	+0.178	+1.070	.002	.007	3	7
BONE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.070	+1.097	.001	.002	3	7
CNS	Regulation of calcineurin-NFAT signaling cascade →	+0.130	+1.172	<.001	<.001	3	7
SOFT_TISSUE	Biological process involved in symbiotic interaction →	+0.099	+0.957	<.001	<.001	3	6
SOFT_TISSUE	Relaxation of smooth muscle →	-0.319	-1.151	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,117 associations by consensus.

Interleukin-9-mediated signaling pathway by GPR85 expression — BLOOD_Lymphoma

Explore this box plot interactively →