GPR84

Across TCGA pan-cancer cohorts, GPR84 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of GPR84’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GPR84 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GPR84 is over-expressed in tumor.

KIRC, HNSC, and KIRP are the cancer types where GPR84 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPR84 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+1.135	<.001	12	view →
HNSC	Male	III,IV	+0.833	<.001	12	view →
KIRP	All	III,IV	+1.076	<.001	11	view →
THCA	All	IV	+1.007	<.001	11	view →
COAD	Male	II,III,IV	+0.967	<.001	10	view →
LUAD	Female	II,III,IV	+1.552	<.001	9	view →
STAD	All	II,III,IV	+0.961	<.001	7	view →
BLCA	All	All	+0.571	.006	7	view →
UCEC	All	III,IV	+1.083	.004	6	view →
BRCA	All	All	+0.968	<.001	6	view →
LUSC	Male	All	+0.719	<.001	6	view →
CHOL	All	All	+1.080	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

GPR84–KIRC

Open the KIRC breakdown →