GPR79

Across TCGA pan-cancer cohorts, GPR79 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated GPR79 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher GPR79 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR79 expression acts as an unfavorable survival marker, although some lineages such as ACC and SKCM show a favorable association.

DLBC, KIRP, and STAD are the cancer types where GPR79 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	All	0.555	0.953	.013	25	view →
KIRP	DFS	Tertile	IV	0.035	0.458	.018	25	view →
STAD	DFS	Quartile	All	0.424	0.580	.021	20	view →
THCA	DFS	Tertile	IV	0.602	0.873	.006	16	view →
MESO	DFS	Tertile	II,III,IV	0.324	0.779	.035	15	view →
PCPG	OS	Quartile	All	0.742	1.000	.001	15	view →
ACC	OS	Tertile	III,IV	0.919	0.434	.008	13	view →
SKCM	OS	Tertile	III,IV	0.592	0.306	.009	12	view →
BRCA	OS	Median	All	0.972	0.953	.017	5	view →
LGG	DFS	Quartile	All	0.880	0.788	.015	5	view →
KIRC	DFS	Tertile	IV	0.252	0.483	.041	4	view →
ESCA	OS	Quartile	II,III,IV	0.326	0.515	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

GPR79–DLBC (DFS)

Open the DLBC breakdown →