GPR75

Across TCGA patient cohorts, GPR75 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,519 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR75-associated proteins across cancer lineages are EEF2_S502, VASP, and PBRM1. Each is linked with GPR75 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR75-to-partner and partner-to-GPR75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR75 versus EEF2_S502 in CCRCC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR75→partner) and Y-score (partner→GPR75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EEF2_S502 →	-0.750	-0.809	<.001	<.001	3	5
GBM	VASP →	-0.376	-0.667	<.001	<.001	3	4
LSCC	PBRM1 →	+0.252	+0.616	<.001	<.001	3	4
GBM	ERO1A →	-0.496	-0.616	<.001	<.001	3	4
LSCC	PRPF19 →	+0.177	+0.538	.001	<.001	3	4
HNSC	GTF3C2 →	+0.245	+0.810	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,519 associations by consensus.

GPR75 vs EEF2_S502 — CCRCC

Explore this scatter interactively →