GPR75-ASB3

Across TCGA pan-cancer cohorts, GPR75-ASB3 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GPR75-ASB3 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher GPR75-ASB3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GPR75-ASB3 expression acts as an unfavorable survival marker, although some lineages such as UCS and READ show a favorable association.

UCS, READ, and MESO are the cancer types where GPR75-ASB3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
READ	OS	Tertile	All	0.970	0.746	.013	22	view →
MESO	OS	Tertile	III,IV	0.871	0.438	.017	21	view →
UVM	DFS	Quartile	III,IV	0.132	0.747	.006	21	view →
CESC	DFS	Tertile	All	0.645	0.789	.010	18	view →
BRCA	DFS	Median	All	0.427	0.591	.002	17	view →
LIHC	OS	Tertile	II,III,IV	0.770	0.524	.010	17	view →
UCEC	DFS	Tertile	IV	0.801	0.353	.021	16	view →
ESCA	OS	Median	All	0.358	0.546	.006	14	view →
KIRP	DFS	Tertile	IV	0.136	0.496	.021	14	view →
COAD	OS	Tertile	III,IV	0.651	0.350	.028	12	view →
LUAD	OS	Tertile	All	0.758	0.628	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GPR75-ASB3–UCS (DFS)

Open the UCS breakdown →