GPR65

Across TCGA patient cohorts, GPR65 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,400 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR65-associated proteins across cancer lineages are RCSD1, RIN3, and SASH3. Each is linked with GPR65 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPR65-to-partner and partner-to-GPR65 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR65 versus RCSD1 in LSCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR65→partner) and Y-score (partner→GPR65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCSD1 →	+0.674	+0.716	<.001	<.001	3	10
GBM	RIN3 →	+0.458	+0.836	<.001	<.001	3	10
GBM	SASH3 →	+0.622	+1.156	<.001	<.001	3	10
GBM	SKAP2 →	+0.867	+1.162	<.001	<.001	3	10
HNSC	ITGAL →	+0.722	+0.912	<.001	<.001	3	10
LSCC	ANKRD44 →	+0.519	+0.804	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,400 associations by consensus.

GPR65 vs RCSD1 — LSCC

Explore this scatter interactively →