GPR63

Across TCGA cell cohorts, GPR63 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,161 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GPR63-associated GO terms across cancer lineages are Heart contraction, 'de novo' IMP biosynthetic process, and RNA 3'-end processing. Each is linked with GPR63 in more than 11 cancer types. Because this analysis shows association rather than direction, both GPR63-to-partner and partner-to-GPR63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heart contraction grouped by GPR63-low versus GPR63-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR63→partner) and Y-score (partner→GPR63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Heart contraction →	-0.114	-0.576	.005	<.001	3	12
OVARY	'de novo' IMP biosynthetic process →	+0.135	+0.986	<.001	<.001	3	12
BONE	RNA 3'-end processing →	+0.084	+1.074	<.001	<.001	3	11
BONE	Positive regulation of DNA metabolic process →	+0.082	+1.165	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.071	+0.437	.002	.004	3	11
BONE	DNA-templated transcription termination →	+0.096	+1.038	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,161 associations by consensus.

Heart contraction by GPR63 expression — OESOPHAGUS

Explore this box plot interactively →