GPR62

Across TCGA patient cohorts, GPR62 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GPR62-associated genes across cancer lineages are ZNF734P, RNA5SP477, and RNU4-36P. Each is linked with GPR62 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR62-to-partner and partner-to-GPR62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF734P grouped by GPR62-low versus GPR62-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR62→partner) and Y-score (partner→GPR62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZNF734P →	+0.338	+4.372	<.001	<.001	3	1
COAD	RNA5SP477 →	+0.961	+3.857	<.001	.003	3	1
COAD	RNU4-36P →	+0.464	+2.984	<.001	.009	3	1
COAD	RPL21P41 →	+0.363	+3.063	.004	.008	3	1
COAD	GUSBP10 →	+0.384	+3.542	<.001	.005	3	1
COAD	LINC00351 →	+0.255	+3.484	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

ZNF734P by GPR62 expression — COAD

Explore this box plot interactively →