GPR62

Across TCGA cell cohorts, GPR62 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR62-associated genes across cancer lineages are DAZ2 and RBMY1J. Each is linked with GPR62 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR62-to-partner and partner-to-GPR62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ2 grouped by GPR62-low versus GPR62-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR62→partner) and Y-score (partner→GPR62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DAZ2 →	+0.336	+5.415	<.001	.004	3	1
LARGE_INTESTINE	RBMY1J →	+0.013	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DAZ2 by GPR62 expression — LARGE_INTESTINE

Explore this box plot interactively →