Across TCGA pan-cancer cohorts, GPR55 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GPR55 data layer compared with 23 for mass-spec protein and 5 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher GPR55 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR55 expression acts as an unfavorable survival marker.
HNSC are the cancer types where GPR55 mass-spec protein most reproducibly stratifies survival.