GPR55

Across TCGA patient cohorts, GPR55 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,372 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR55-associated proteins across cancer lineages are NFATC2, HCLS1, and SAMHD1. Each is linked with GPR55 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPR55-to-partner and partner-to-GPR55 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR55 versus NFATC2 in GBM, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR55→partner) and Y-score (partner→GPR55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NFATC2 →	+0.426	+0.612	<.001	<.001	3	8
GBM	HCLS1 →	+0.705	+0.533	<.001	.002	3	8
UCEC	SAMHD1 →	+0.520	+0.752	.001	.004	3	8
CCRCC	TRAF1 →	+0.482	+0.356	.002	.001	3	7
BRCA	CORO1A →	+0.603	+0.397	<.001	<.001	3	7
LSCC	DOCK10 →	+0.452	+0.380	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,372 associations by consensus.

GPR55 vs NFATC2 — GBM

Explore this scatter interactively →