GPR55

Across TCGA patient cohorts, GPR55 protein abundance is significantly associated with the RNA expression of many other genes, with 411 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPR55-associated genes across cancer lineages are EEF1A2, MYLK2, and TNNC2. Each is linked with GPR55 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR55-to-partner and partner-to-GPR55 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR55 versus EEF1A2 in HNSC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR55→partner) and Y-score (partner→GPR55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EEF1A2 →	+3.148	+2.626	<.001	<.001	3	1
HNSC	MYLK2 →	+2.472	+3.780	.003	<.001	3	1
HNSC	TNNC2 →	+5.186	+3.096	.002	.004	3	1
HNSC	MYOM1 →	+3.046	+3.166	.001	.002	3	1
HNSC	ST8SIA5 →	+0.356	+3.090	<.001	<.001	3	1
HNSC	ATP1B4 →	+2.968	+3.757	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 411 associations by consensus.

GPR55 vs EEF1A2 — HNSC

Explore this scatter interactively →