Across TCGA cell cohorts, GPR52 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GPR52-associated genes across cancer lineages are OR4M1, IQCF2, and RNASE9. Each is linked with GPR52 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR52-to-partner and partner-to-GPR52 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR52→partner) and Y-score (partner→GPR52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR4M1 →	+0.036	+5.169	<.001	.005	3	1
BREAST	IQCF2 →	+0.043	+5.781	<.001	.001	3	1
LUNG_SCLC	RNASE9 →	+0.029	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

GPR52 survival (RNA) · tumor vs normal (RNA) · all GPR52 data types