GPR50-AS1

Across TCGA pan-cancer cohorts, GPR50-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated GPR50-AS1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher GPR50-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR50-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

STAD, UCS, and LUSC are the cancer types where GPR50-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.209	0.443	.006	69	view →
UCS	DFS	Median	II,III,IV	0.552	0.136	.001	56	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	39	view →
LIHC	OS	Tertile	All	0.189	0.674	.003	36	view →
ACC	DFS	Tertile	III,IV	0.046	0.670	.001	33	view →
DLBC	OS	Tertile	III,IV	0.154	0.735	.010	28	view →
PAAD	DFS	Tertile	All	0.099	0.473	<.001	27	view →
LUAD	OS	Tertile	IV	0.174	0.597	.044	18	view →
PCPG	DFS	Tertile	All	0.107	0.890	.003	15	view →
KIRP	OS	Tertile	All	0.828	0.951	.009	12	view →
ESCA	DFS	Quartile	II,III,IV	0.246	0.397	.016	10	view →
LGG	OS	Median	All	0.939	0.860	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

GPR50-AS1–STAD (DFS)

Open the STAD breakdown →