GPR42

Across TCGA patient cohorts, GPR42 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,586 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR42-associated GO terms across cancer lineages are Mononuclear cell migration, Regulation of CD4-positive, alpha-beta T cell activation, and Tumor necrosis factor superfamily cytokine production. Each is linked with GPR42 in more than 20 cancer types. Because this analysis shows association rather than direction, both GPR42-to-partner and partner-to-GPR42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mononuclear cell migration grouped by GPR42-low versus GPR42-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR42→partner) and Y-score (partner→GPR42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mononuclear cell migration →	+0.076	+0.082	<.001	<.001	3	20
ESCA	Regulation of CD4-positive, alpha-beta T cell activation →	+0.062	+0.090	<.001	.001	3	20
ESCA	Tumor necrosis factor superfamily cytokine production →	+0.063	+0.086	<.001	<.001	3	19
PCPG	Astrocyte cell migration →	+0.075	+0.087	<.001	<.001	2	20
STAD	Regulation of leukocyte migration →	+0.053	+0.058	<.001	<.001	3	19
DLBC	Neuroinflammatory response →	+0.060	+0.128	.004	.006	1	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,586 associations by consensus.

Mononuclear cell migration by GPR42 expression — ESCA

Explore this box plot interactively →