GPR42

Across TCGA cell cohorts, GPR42 RNA expression is significantly associated with the mutation status of many other genes, with 91 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GPR42-associated genes across cancer lineages are MAN2A2, WASHC2A, and KIF21A. Each is linked with GPR42 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR42-to-partner and partner-to-GPR42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAN2A2 grouped by GPR42-low versus GPR42-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR42→partner) and Y-score (partner→GPR42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MAN2A2 →	+5.369	+0.026	.004	<.001	3	2
STOMACH	WASHC2A →	+4.247	+0.013	<.001	<.001	3	2
LIVER	KIF21A →	+3.459	+0.006	.004	<.001	3	1
LIVER	MCTP2 →	+3.459	+0.006	.004	<.001	3	1
OESOPHAGUS	BCAT1 →	+4.017	+0.024	.007	<.001	3	1
LIVER	TPTE →	+3.459	+0.006	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

MAN2A2 by GPR42 expression — SOFT_TISSUE

Explore this box plot interactively →