GPR4

Across TCGA patient cohorts, GPR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,163 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GPR4-associated proteins across cancer lineages are CD93, ITIH3, and LAMA4. Each is linked with GPR4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR4-to-partner and partner-to-GPR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR4 versus CD93 in CCRCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR4→partner) and Y-score (partner→GPR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CD93 →	+0.587	+0.678	<.001	<.001	3	9
OV	ITIH3 →	+0.959	+0.931	<.001	<.001	3	7
OV	LAMA4 →	+0.646	+0.909	<.001	<.001	3	7
UCEC	MCAM →	+0.589	+1.181	<.001	<.001	3	7
BRCA	COL1A2 →	+0.735	+0.636	<.001	<.001	3	7
OV	FN1 →	+1.058	+0.778	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,163 associations by consensus.

GPR4 vs CD93 — CCRCC

Explore this scatter interactively →