GPR4

Across TCGA cell cohorts, GPR4 RNA expression is significantly associated with the RNA expression of many other genes, with 3,110 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GPR4-associated genes across cancer lineages are TFPI2, ARID3A, and SPEM1. Each is linked with GPR4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR4-to-partner and partner-to-GPR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR4 versus TFPI2 in SKIN, with a Pearson correlation of 0.41.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR4→partner) and Y-score (partner→GPR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TFPI2 →	+2.519	+0.189	<.001	.006	3	3
BLOOD_Leukemia	ARID3A →	+1.014	+0.069	<.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	SPEM1 →	+0.083	+0.061	.003	.008	3	2
UPPER_AERODIGESTIVE_TRACT	EBLN1 →	+0.041	+0.070	<.001	<.001	3	2
BONE	CHP1 →	+0.928	+0.401	<.001	.006	3	2
SOFT_TISSUE	PCNX3 →	+0.849	+0.948	<.001	.005	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,110 associations by consensus.

GPR4 vs TFPI2 — SKIN

Explore this scatter interactively →