Across TCGA patient cohorts, GPR39 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,801 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR39-associated proteins across cancer lineages are GPR39_S396, VAV2, and PHGDH. Each is linked with GPR39 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR39-to-partner and partner-to-GPR39 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR39→partner) and Y-score (partner→GPR39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GPR39_S396 →	+1.787	+1.429	<.001	<.001	3	5
COAD	VAV2 →	+0.329	+0.557	.001	.001	3	4
HNSC	PHGDH →	-0.758	-1.358	<.001	<.001	3	4
COAD	PRDX5 →	+0.520	+0.478	<.001	<.001	3	4
GBM	VAMP8 →	+0.580	+0.704	.001	.001	3	4
UCEC	S100A11 →	+0.470	+0.604	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,801 associations by consensus.

Exploration

GPR39 survival (RNA) · tumor vs normal (RNA) · all GPR39 data types