GPR37

Across TCGA pan-cancer cohorts, GPR37 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GPR37 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GPR37 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GPR37 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SARC show a favorable association.

LUAD, BLCA, and OV are the cancer types where GPR37 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.099	0.682	<.001	26	view →
BLCA	OS	Median	All	0.090	0.688	<.001	24	view →
OV	DFS	Median	All	0.104	0.541	<.001	18	view →
UCEC	DFS	Median	All	0.970	0.828	.020	14	view →
SARC	OS	Median	All	1.000	0.493	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GPR37–LUAD (OS)

Open the LUAD breakdown →