GPR37

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GPR37 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,521 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPR37-associated GO terms across cancer lineages are Endosomal lumen acidification, Aerobic respiration, and Cellular respiration. Each is linked with GPR37 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPR37-to-partner and partner-to-GPR37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal lumen acidification grouped by GPR37-low versus GPR37-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR37→partner) and Y-score (partner→GPR37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHEndosomal lumen acidification →+0.150+1.790.002<.00138
SOFT_TISSUEAerobic respiration →+0.061+0.994<.001<.00138
BLOOD_LymphomaCellular respiration →+0.074+0.334<.001.00137
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.151+1.257<.001<.00137
STOMACHHost-mediated activation of viral genome replication →+0.110+1.437.001<.00137
STOMACHEndoplasmic reticulum to Golgi vesicle-mediated transport →+0.066+1.264.002.00128
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,521 associations by consensus.

Endosomal lumen acidification by GPR37 expression — STOMACH

Box plot of Endosomal lumen acidification in GPR37-low vs GPR37-high samples in STOMACH.

Explore this box plot interactively →

Exploration