GPR34

Across TCGA patient cohorts, GPR34 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,917 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR34-associated proteins across cancer lineages are EVL, KCTD12, and AIF1. Each is linked with GPR34 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPR34-to-partner and partner-to-GPR34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR34 versus EVL in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR34→partner) and Y-score (partner→GPR34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EVL →	+0.999	+0.916	<.001	<.001	3	10
UCEC	KCTD12 →	+0.561	+0.612	<.001	<.001	3	9
GBM	AIF1 →	+0.813	+1.072	<.001	<.001	3	8
HNSC	FOLR2 →	+0.849	+0.754	<.001	<.001	3	8
GBM	HCLS1 →	+0.755	+1.030	<.001	<.001	3	8
COAD	PLEKHO2 →	+0.486	+0.967	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,917 associations by consensus.

GPR34 vs EVL — HNSC

Explore this scatter interactively →