GPR34

Across TCGA patient cohorts, GPR34 protein abundance is significantly associated with the RNA expression of many other genes, with 1,255 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR34-associated genes across cancer lineages are CYTH4, MFNG, and CRYBB1. Each is linked with GPR34 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR34-to-partner and partner-to-GPR34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR34 versus CYTH4 in GBM, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR34→partner) and Y-score (partner→GPR34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.049	+0.825	<.001	<.001	3	1
GBM	MFNG →	+1.173	+0.781	<.001	.003	3	1
GBM	CRYBB1 →	+1.066	+0.933	.001	.002	3	1
GBM	AP1B1 →	+0.775	+0.929	.004	.001	3	1
GBM	GRAP2 →	+0.425	+0.678	.009	.006	3	1
GBM	NCF4 →	+1.031	+0.825	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,255 associations by consensus.

GPR34 vs CYTH4 — GBM

Explore this scatter interactively →