GPR32

Across TCGA cell cohorts, GPR32 RNA expression is significantly associated with the go_rna of many other GO terms, with 620 significant associations in total. CNS shows the largest number of these associations.

The most reproducible GPR32-associated GO terms across cancer lineages are Purine ribonucleotide biosynthetic process, Purine ribonucleoside triphosphate metabolic process, and Spliceosomal snRNP assembly. Each is linked with GPR32 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR32-to-partner and partner-to-GPR32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide biosynthetic process grouped by GPR32-low versus GPR32-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR32→partner) and Y-score (partner→GPR32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Purine ribonucleotide biosynthetic process →	+0.057	+0.024	<.001	.002	3	5
BREAST	Purine ribonucleoside triphosphate metabolic process →	+0.064	+0.016	<.001	.002	3	5
LUNG_NSCLC_LUSC	Spliceosomal snRNP assembly →	+0.063	+0.044	.006	.008	3	5
LIVER	Regulation of double-strand break repair →	+0.068	+0.015	<.001	.008	3	4
BREAST	Electron transport chain →	+0.077	+0.015	<.001	.004	3	4
BREAST	ATP synthesis coupled electron transport →	+0.078	+0.015	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 620 associations by consensus.

Purine ribonucleotide biosynthetic process by GPR32 expression — BLOOD_Leukemia

Explore this box plot interactively →