GPR3

Across TCGA cell cohorts, GPR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,714 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPR3-associated GO terms across cancer lineages are Gluconeogenesis, Nuclear chromosome segregation, and Pyrimidine-containing compound biosynthetic process. Each is linked with GPR3 in more than 12 cancer types. Because this analysis shows association rather than direction, both GPR3-to-partner and partner-to-GPR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gluconeogenesis grouped by GPR3-low versus GPR3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR3→partner) and Y-score (partner→GPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Gluconeogenesis →	+0.107	+1.010	<.001	.008	3	13
UPPER_AERODIGESTIVE_TRACT	Nuclear chromosome segregation →	+0.107	+0.727	.002	.006	3	12
UPPER_AERODIGESTIVE_TRACT	Pyrimidine-containing compound biosynthetic process →	+0.099	+0.660	<.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	DNA synthesis involved in DNA repair →	+0.087	+0.921	<.001	.001	3	12
OESOPHAGUS	Regulation of centrosome cycle →	+0.091	+1.156	.008	.002	3	11
SKIN	Hexose biosynthetic process →	+0.111	+1.325	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,714 associations by consensus.

Gluconeogenesis by GPR3 expression — STOMACH

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