GPR25

Across TCGA patient cohorts, GPR25 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,589 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR25-associated proteins across cancer lineages are CD2, DOCK10, and ARHGAP45. Each is linked with GPR25 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPR25-to-partner and partner-to-GPR25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR25 versus CD2 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR25→partner) and Y-score (partner→GPR25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD2 →	+0.918	+0.387	<.001	.002	3	8
LSCC	DOCK10 →	+0.474	+0.564	<.001	<.001	3	8
UCEC	ARHGAP45 →	+0.553	+0.646	<.001	<.001	3	7
LSCC	MYO1G →	+0.472	+0.497	<.001	<.001	3	7
PDAC	SPN_S355 →	+0.795	+0.249	<.001	<.001	3	7
BRCA	CD8A →	+0.997	+0.452	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,589 associations by consensus.

GPR25 vs CD2 — BRCA

Explore this scatter interactively →