GPR25

Across TCGA patient cohorts, GPR25 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR25-associated genes across cancer lineages are MPP, Adipocytes, and DC. Each is linked with GPR25 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR25-to-partner and partner-to-GPR25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by GPR25-low versus GPR25-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR25→partner) and Y-score (partner→GPR25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.026	+2.818	.003	.023	3	2
UCEC	Adipocytes →	+0.037	+2.507	<.001	.022	3	2
UCEC	DC →	+0.026	+2.871	.038	.034	3	2

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MPP by GPR25 expression — COAD

Explore this box plot interactively →