GPR22

Across TCGA patient cohorts, GPR22 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,369 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR22-associated proteins across cancer lineages are PUS7, MEAK7, and MVP. Each is linked with GPR22 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR22-to-partner and partner-to-GPR22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR22 versus PUS7 in LUAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR22→partner) and Y-score (partner→GPR22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PUS7 →	+0.414	+0.556	<.001	<.001	3	5
LSCC	MEAK7 →	-0.386	-0.409	<.001	<.001	3	4
GBM	MVP →	-0.434	-0.341	<.001	<.001	3	3
LSCC	AQR →	+0.324	+0.663	<.001	<.001	3	3
LSCC	NELFB →	+0.230	+0.547	<.001	<.001	3	3
LSCC	NOM1 →	+0.355	+0.548	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,369 associations by consensus.

GPR22 vs PUS7 — LUAD

Explore this scatter interactively →