Across TCGA pan-cancer cohorts, GPR19 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GPR19 data layer compared with 30 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher GPR19 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GPR19 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

ESCA, UCEC, and ACC are the cancer types where GPR19 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	All	0.141	0.700	.001	9	view →
UCEC	OS	Median	All	1.000	0.660	.027	6	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: GPR19 tumor-vs-normal RNA expression · all GPR19 data types