GPR183

Across TCGA patient cohorts, GPR183 protein abundance is significantly associated with the RNA expression of many other genes, with 4,240 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR183-associated genes across cancer lineages are NCF4, CSF2RB, and CD79A. Each is linked with GPR183 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR183-to-partner and partner-to-GPR183 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR183 versus NCF4 in GBM, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR183→partner) and Y-score (partner→GPR183) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCF4 →	+1.754	+1.081	.001	<.001	3	3
GBM	CSF2RB →	+1.780	+1.081	.003	<.001	3	3
LSCC	CD79A →	+1.913	+0.952	<.001	<.001	3	3
GBM	CYTIP →	+1.485	+1.081	.003	<.001	3	3
GBM	ITGA4 →	+1.898	+1.081	.004	<.001	3	3
GBM	THEMIS2 →	+1.739	+1.081	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

GPR183 vs NCF4 — GBM

Explore this scatter interactively →