GPR182

Across TCGA cell cohorts, GPR182 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,704 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR182-associated GO terms across cancer lineages are Heterochromatin organization, Heterochromatin formation, and Negative regulation of gene expression, epigenetic. Each is linked with GPR182 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPR182-to-partner and partner-to-GPR182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by GPR182-low versus GPR182-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR182→partner) and Y-score (partner→GPR182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heterochromatin organization →	+0.071	+0.104	<.001	<.001	3	10
BONE	Heterochromatin formation →	+0.075	+0.104	<.001	<.001	3	10
BONE	Negative regulation of gene expression, epigenetic →	+0.075	+0.104	<.001	<.001	3	9
LARGE_INTESTINE	Pre-miRNA processing →	+0.087	+0.113	<.001	<.001	3	9
BONE	Subtelomeric heterochromatin formation →	+0.121	+0.102	<.001	<.001	3	9
BONE	Epigenetic regulation of gene expression →	+0.067	+0.100	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,704 associations by consensus.

Heterochromatin organization by GPR182 expression — BONE

Explore this box plot interactively →