GPR180

Across TCGA pan-cancer cohorts, GPR180 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GPR180 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher GPR180 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GPR180 expression acts as an unfavorable survival marker.

LSCC, CCRCC, and LUAD are the cancer types where GPR180 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.778	1.000	.005	13	view →
CCRCC	DFS	Tertile	III,IV	0.302	0.765	.020	6	view →
LUAD	OS	Quartile	II,III,IV	0.280	0.711	.022	4	view →
PDAC	OS	Median	III,IV	0.231	0.426	.035	3	view →
GBM	DFS	Quartile	All	0.245	0.485	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GPR180–LSCC (OS)

Open the LSCC breakdown →