GPR180

Across TCGA patient cohorts, GPR180 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,734 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR180-associated proteins across cancer lineages are IPO5, ARHGEF7, and COQ9. Each is linked with GPR180 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR180-to-partner and partner-to-GPR180 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR180 versus IPO5 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR180→partner) and Y-score (partner→GPR180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	IPO5 →	+0.359	+0.465	<.001	<.001	3	5
LSCC	ARHGEF7 →	+0.273	+0.656	<.001	<.001	3	4
OV	COQ9 →	-0.575	-0.415	<.001	.007	3	4
GBM	RBM26 →	+0.281	+0.486	<.001	<.001	3	4
LSCC	TUBGCP3 →	+0.332	+0.679	<.001	<.001	3	4
COAD	ACSF3 →	-0.320	-0.426	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,734 associations by consensus.

GPR180 vs IPO5 — PDAC

Explore this scatter interactively →