GPR180

Across TCGA patient cohorts, GPR180 protein abundance is significantly associated with the RNA expression of many other genes, with 14,290 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR180-associated genes across cancer lineages are CALCOCO1, CARF, and CENPC. Each is linked with GPR180 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPR180-to-partner and partner-to-GPR180 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR180 versus CALCOCO1 in UCEC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR180→partner) and Y-score (partner→GPR180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CALCOCO1 →	-0.393	-0.531	.003	<.001	3	5
HNSC	CARF →	-0.505	-0.337	.006	.003	3	5
GBM	CENPC →	-0.437	-0.482	<.001	<.001	3	5
LUAD	GNAQ →	-0.515	-0.493	<.001	<.001	3	5
LSCC	ZNF250 →	-0.585	-0.373	<.001	<.001	3	5
HNSC	ZNF846 →	-0.607	-0.364	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,290 associations by consensus.

GPR180 vs CALCOCO1 — UCEC

Explore this scatter interactively →