GPR180

Across TCGA patient cohorts, GPR180 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,647 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GPR180-associated proteins across cancer lineages are LMAN1, NCLN, and RAB43. Each is linked with GPR180 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPR180-to-partner and partner-to-GPR180 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR180 versus LMAN1 in UCEC, with a Pearson correlation of 0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR180→partner) and Y-score (partner→GPR180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LMAN1 →	+0.491	+0.716	<.001	<.001	3	7
UCEC	NCLN →	+0.561	+0.755	<.001	<.001	3	7
UCEC	RAB43 →	+0.384	+0.593	<.001	<.001	3	7
UCEC	RPN1 →	+0.510	+0.624	<.001	<.001	3	6
UCEC	RPN2 →	+0.563	+0.684	<.001	<.001	3	6
PDAC	SEC61A1 →	+0.573	+0.557	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,647 associations by consensus.

GPR180 vs LMAN1 — UCEC

Explore this scatter interactively →