Across TCGA cell cohorts, GPR173 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR173-associated genes across cancer lineages are TACR3, OC90, and OR1D4. Each is linked with GPR173 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR173-to-partner and partner-to-GPR173 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR173→partner) and Y-score (partner→GPR173) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TACR3 →	+0.038	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OC90 →	+0.012	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.152	+4.087	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

GPR173 survival (RNA) · tumor vs normal (RNA) · all GPR173 data types