GPR171

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPR171 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,500 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPR171-associated proteins across cancer lineages are RASAL3, ARHGAP45, and ARHGAP9_S475. Each is linked with GPR171 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR171-to-partner and partner-to-GPR171 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR171 versus RASAL3 in OV, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR171→partner) and Y-score (partner→GPR171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRASAL3 →+0.555+0.949<.001<.00139
UCECARHGAP45 →+0.629+1.243<.001<.00139
HNSCARHGAP9_S475 →+0.825+1.110<.001<.00139
UCECPSMB10 →+0.502+0.949<.001.00339
LSCCPSMB6 →-0.437-0.842<.001<.00139
OVPTPRC →+0.809+1.388<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,500 associations by consensus.

GPR171 vs RASAL3 — OV

Per-sample scatter of GPR171 vs RASAL3 in OV (Pearson r = 0.67).

Explore this scatter interactively →

Exploration