GPR171

Across TCGA cell cohorts, GPR171 RNA expression is significantly associated with the go_rna of many other GO terms, with 893 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPR171-associated GO terms across cancer lineages are Positive regulation of neuron projection development, Transsulfuration, and Regulation of non-canonical Wnt signaling pathway. Each is linked with GPR171 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR171-to-partner and partner-to-GPR171 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of neuron projection development grouped by GPR171-low versus GPR171-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR171→partner) and Y-score (partner→GPR171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of neuron projection development →	-0.068	-0.018	<.001	.007	3	3
LARGE_INTESTINE	Transsulfuration →	+0.157	+0.012	.004	.009	3	3
BLOOD_Lymphoma	Regulation of non-canonical Wnt signaling pathway →	+0.109	+1.752	<.001	<.001	3	3
BLOOD_Lymphoma	Negative regulation of stem cell differentiation →	+0.062	+2.127	<.001	<.001	3	3
BLOOD_Lymphoma	Protein transport within lipid bilayer →	-0.210	-1.751	<.001	.005	3	3
URINARY_TRACT	Metanephric tubule formation →	-1.644	-0.018	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 893 associations by consensus.

Positive regulation of neuron projection development by GPR171 expression — URINARY_TRACT

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