GPR162

Across TCGA patient cohorts, GPR162 mutation is significantly associated with the RNA expression of many other genes, with 1,704 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR162-associated genes across cancer lineages are NQO2-AS1, MRPS5P3, and CHAF1B. Each is linked with GPR162 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR162-to-partner and partner-to-GPR162 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NQO2-AS1 grouped by GPR162-low versus GPR162-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR162→partner) and Y-score (partner→GPR162) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NQO2-AS1 →	+0.398	+3.392	<.001	.004	3	2
KIRP	MRPS5P3 →	+0.290	+5.060	<.001	.008	3	2
UCEC	CHAF1B →	+0.594	+3.823	.001	<.001	3	2
UCEC	MFSD12 →	+0.490	+2.463	.001	.001	3	2
UCEC	FAM102A →	+0.532	+2.108	.001	.003	3	2
UCEC	SLC27A4 →	+0.444	+2.584	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,704 associations by consensus.

NQO2-AS1 by GPR162 expression — SKCM

Explore this box plot interactively →