GPR162

Across TCGA cell cohorts, GPR162 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPR162-associated genes across cancer lineages are C4BPA, ANKRD30BL, and ADAM18. Each is linked with GPR162 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR162-to-partner and partner-to-GPR162 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C4BPA grouped by GPR162-low versus GPR162-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR162→partner) and Y-score (partner→GPR162) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C4BPA →	+0.039	+4.054	<.001	.004	3	1
SKIN	ANKRD30BL →	+0.072	+3.684	<.001	.006	3	1
SKIN	ADAM18 →	+0.061	+4.196	<.001	.002	3	1
SKIN	OR5A1 →	+0.012	+4.437	<.001	.004	3	1
SKIN	HES5 →	+0.047	+4.155	.003	.003	3	1
CNS	GNG8 →	+1.168	+3.643	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C4BPA by GPR162 expression — SKIN

Explore this box plot interactively →