GPR153

Across TCGA cell cohorts, GPR153 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,199 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GPR153-associated GO terms across cancer lineages are Fat cell proliferation, Hippocampus development, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with GPR153 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR153-to-partner and partner-to-GPR153 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fat cell proliferation grouped by GPR153-low versus GPR153-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR153→partner) and Y-score (partner→GPR153) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Fat cell proliferation →	-0.377	-1.368	<.001	.006	3	8
KIDNEY	Hippocampus development →	+0.083	+1.078	<.001	<.001	2	9
SOFT_TISSUE	Positive regulation of double-strand break repair via homologous recombination →	+0.101	+1.918	<.001	<.001	3	8
STOMACH	Cell division →	+0.079	+1.733	.002	<.001	3	7
PANCREAS	Negative regulation of cilium assembly →	+0.047	+1.218	.007	.001	3	7
KIDNEY	Limbic system development →	+0.083	+1.089	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,199 associations by consensus.

Fat cell proliferation by GPR153 expression — LIVER

Explore this box plot interactively →