GPR151

Across TCGA patient cohorts, GPR151 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,158 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GPR151-associated proteins across cancer lineages are VIM_S430, SF3B1_T426, and IRF2BP1_S186. Each is linked with GPR151 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPR151-to-partner and partner-to-GPR151 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR151 versus VIM_S430 in CCRCC, with a Pearson correlation of -0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR151→partner) and Y-score (partner→GPR151) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VIM_S430 →	-0.482	-0.240	<.001	<.001	3	6
HNSC	SF3B1_T426 →	+0.477	+0.658	<.001	<.001	3	5
LSCC	IRF2BP1_S186 →	+0.729	+0.185	<.001	<.001	3	5
HNSC	AP4B1_S593 →	-0.663	-0.472	<.001	<.001	3	5
PDAC	STIM1_S257 →	-0.885	-0.237	<.001	<.001	3	5
LSCC	STIM2_S261 →	-0.649	-0.284	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,158 associations by consensus.

GPR151 vs VIM_S430 — CCRCC

Explore this scatter interactively →