GPR151

Across TCGA cell cohorts, GPR151 RNA expression is significantly associated with the go_rna of many other GO terms, with 697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR151-associated GO terms across cancer lineages are Regulation of chromatin organization, Regulation of ubiquitin protein ligase activity, and Spliceosomal complex assembly. Each is linked with GPR151 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPR151-to-partner and partner-to-GPR151 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by GPR151-low versus GPR151-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR151→partner) and Y-score (partner→GPR151) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of chromatin organization →	+0.086	+0.028	.006	.006	3	7
PANCREAS	Regulation of ubiquitin protein ligase activity →	+0.072	+0.008	.002	.004	3	5
CNS	Spliceosomal complex assembly →	+0.055	+0.015	.003	.001	3	4
OVARY	Regulation of calcium import into the mitochondrion →	+0.145	+0.013	.001	.006	3	4
OVARY	Leading strand elongation →	+0.134	+0.009	.002	.004	2	5
CNS	Negative regulation of potassium ion transport →	-0.121	-0.015	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 697 associations by consensus.

Regulation of chromatin organization by GPR151 expression — BONE

Explore this box plot interactively →