GPR15

Across TCGA patient cohorts, GPR15 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,681 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR15-associated proteins across cancer lineages are GIMAP7, SEPTIN1, and ARHGAP25. Each is linked with GPR15 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR15-to-partner and partner-to-GPR15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR15 versus GIMAP7 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR15→partner) and Y-score (partner→GPR15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GIMAP7 →	+0.585	+1.446	<.001	<.001	3	9
OV	SEPTIN1 →	+0.909	+0.673	<.001	<.001	3	8
OV	ARHGAP25 →	+0.804	+0.525	.002	.002	3	8
OV	ARHGAP45 →	+0.763	+0.779	<.001	<.001	3	8
OV	ADA2 →	+0.654	+0.684	<.001	<.001	3	8
OV	GPSM3 →	+0.579	+0.437	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,681 associations by consensus.

GPR15 vs GIMAP7 — LSCC

Explore this scatter interactively →