GPR15

Across TCGA cell cohorts, GPR15 RNA expression is significantly associated with the go_rna of many other GO terms, with 904 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPR15-associated GO terms across cancer lineages are Regulation of adaptive immune response, Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, and Regulation of programmed necrotic cell death. Each is linked with GPR15 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR15-to-partner and partner-to-GPR15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of adaptive immune response grouped by GPR15-low versus GPR15-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR15→partner) and Y-score (partner→GPR15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of adaptive immune response →	+0.062	+2.716	<.001	<.001	3	4
BLOOD_Lymphoma	Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	+0.057	+2.526	<.001	<.001	3	4
BLOOD_Lymphoma	Regulation of programmed necrotic cell death →	+0.056	+2.001	.004	.007	3	4
BLOOD_Lymphoma	Cell surface receptor signaling pathway via STAT →	+0.052	+2.112	.001	<.001	3	4
BLOOD_Leukemia	Positive regulation of canonical NF-kappaB signal transduction →	+0.022	+1.152	.007	.005	3	4
BLOOD_Lymphoma	Detection of bacterium →	+0.152	+2.040	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 904 associations by consensus.

Regulation of adaptive immune response by GPR15 expression — BLOOD_Lymphoma

Explore this box plot interactively →