GPR146

Across TCGA patient cohorts, GPR146 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR146-associated proteins across cancer lineages are CAB39, FOXK1, and NUDT1. Each is linked with GPR146 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR146-to-partner and partner-to-GPR146 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR146 versus CAB39 in HNSC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR146→partner) and Y-score (partner→GPR146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CAB39 →	-0.261	-0.272	<.001	.002	3	5
LSCC	FOXK1 →	+0.377	+0.496	<.001	<.001	3	5
LSCC	NUDT1 →	+0.322	+0.354	<.001	<.001	3	4
COAD	COPZ1 →	-0.345	-0.240	<.001	<.001	3	4
COAD	GAK →	-0.181	-0.225	<.001	<.001	3	4
BRCA	GCN1 →	-0.311	-0.314	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,410 associations by consensus.

GPR146 vs CAB39 — HNSC

Explore this scatter interactively →