Across TCGA cell cohorts, GPR141 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,757 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR141-associated GO terms across cancer lineages are Protein folding in endoplasmic reticulum, Regulation of viral genome replication, and Regulation of MHC class II biosynthetic process. Each is linked with GPR141 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR141-to-partner and partner-to-GPR141 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR141→partner) and Y-score (partner→GPR141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein folding in endoplasmic reticulum →	+0.068	+0.021	.001	.001	3	3
OVARY	Regulation of viral genome replication →	+0.079	+0.994	.001	.003	3	3
OVARY	Regulation of MHC class II biosynthetic process →	+0.118	+0.681	<.001	.008	3	3
BLOOD_Leukemia	Regulation of postsynaptic cytosolic calcium ion concentration →	+0.866	+1.210	<.001	<.001	3	3
BLOOD_Leukemia	Positive regulation of plasma cell differentiation →	+0.134	+1.187	<.001	<.001	3	3
BLOOD_Leukemia	Positive regulation of phospholipid metabolic process →	+0.153	+1.333	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,757 associations by consensus.

Exploration

GPR141 survival (RNA) · tumor vs normal (RNA) · all GPR141 data types