GPR139

Across TCGA patient cohorts, GPR139 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,778 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR139-associated GO terms across cancer lineages are Ovarian follicle development, Cellular pigmentation, and Positive regulation by host of viral transcription. Each is linked with GPR139 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPR139-to-partner and partner-to-GPR139 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ovarian follicle development grouped by GPR139-low versus GPR139-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR139→partner) and Y-score (partner→GPR139) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ovarian follicle development →	+0.034	+0.051	<.001	<.001	3	7
STAD	Cellular pigmentation →	+0.060	+0.053	<.001	<.001	3	7
STAD	Positive regulation by host of viral transcription →	+0.061	+0.058	<.001	<.001	3	7
STAD	Establishment of protein localization to chromosome →	+0.057	+0.056	<.001	<.001	3	7
STAD	Receptor clustering →	+0.037	+0.052	<.001	<.001	3	7
STAD	Membrane biogenesis →	+0.072	+0.055	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,778 associations by consensus.

Ovarian follicle development by GPR139 expression — STAD

Explore this box plot interactively →