GPR139

Across TCGA patient cohorts, GPR139 protein abundance is significantly associated with the RNA expression of many other genes, with 1,347 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR139-associated genes across cancer lineages are NEFH, RASD2, and SYNGR1. Each is linked with GPR139 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR139-to-partner and partner-to-GPR139 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR139 versus NEFH in GBM, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR139→partner) and Y-score (partner→GPR139) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEFH →	+1.364	+0.895	<.001	<.001	3	1
GBM	RASD2 →	+0.888	+1.043	.001	.003	3	1
GBM	SYNGR1 →	+1.053	+1.022	.004	.005	3	1
GBM	CACNA1I →	+0.772	+0.981	<.001	<.001	3	1
GBM	KIAA0930 →	+0.846	+1.221	<.001	<.001	3	1
GBM	CHGA →	+2.279	+1.326	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,347 associations by consensus.

GPR139 vs NEFH — GBM

Explore this scatter interactively →