GPR137

Across TCGA patient cohorts, GPR137 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,155 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPR137-associated GO terms across cancer lineages are Alpha-linolenic acid metabolic process, Axoneme assembly, and Negative regulation of protein localization to chromatin. Each is linked with GPR137 in more than 19 cancer types. Because this analysis shows association rather than direction, both GPR137-to-partner and partner-to-GPR137 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alpha-linolenic acid metabolic process grouped by GPR137-low versus GPR137-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR137→partner) and Y-score (partner→GPR137) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Alpha-linolenic acid metabolic process →	+0.062	+0.418	<.001	<.001	3	20
GBM	Axoneme assembly →	+0.036	+0.238	<.001	.005	3	19
LAML	Negative regulation of protein localization to chromatin →	+0.062	+0.519	<.001	<.001	3	18
LAML	Methylglyoxal metabolic process →	+0.046	+0.523	<.001	<.001	3	18
ACC	Isopentenyl diphosphate biosynthetic process →	+0.066	+0.921	.009	.002	1	20
READ	Sperm mitochondrial sheath assembly →	-0.082	-0.433	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

Alpha-linolenic acid metabolic process by GPR137 expression — LAML

Explore this box plot interactively →